Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436521 | 0.90 | DAGLA (0.47) | ESR1ESR2DAGLATAS2R14C5AR1 | |
| SCHEMBL11060281 | 0.85 | TAS2R14 (0.50) | ESR1DAGLATAS2R14C5AR1RAB9A | |
| SCHEMBL11065802 | 0.84 | TAS2R14 (0.49) | ESR1DAGLATAS2R14C5AR1RAB9A | |
| SCHEMBL11063373 | 0.84 | CNR2 (0.46) | ESR1DAGLATAS2R14C5AR1CCR5 | |
| SCHEMBL11442725 | 0.82 | S1PR1 (0.44) | ESR1DAGLATAS2R14C5AR1RAB9A | |
| SCHEMBL7704844 | 0.80 | TSHR (0.39) | ESR1DAGLATAS2R14C5AR1RAB9A | |
| SCHEMBL11062327 | 0.77 | C5AR1 (0.38) | ESR1DAGLATAS2R14C5AR1RAB9A | |
| SCHEMBL11067369 | 0.76 | ESR2 (0.47) | ESR1ESR2DAGLATAS2R14 | |
| SCHEMBL11439451 | 0.74 | S1PR1 (0.41) | ESR1ESR2C5AR1RAB9ACCR5 | |
| SCHEMBL9277957 | 0.72 | ESR1 (0.62) | ESR1TAS2R14C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468245-A | N-(2,3-Epoxypropylene)-n-aralkylsulfonamide and herbicidal compositions containing the same | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1984-08-28 | — | — | US | disclosed |