Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436521 | 0.86 | DAGLA (0.47) | TSHRDAGLAC5AR1ESR1TAS2R14 | |
| SCHEMBL11062327 | 0.81 | C5AR1 (0.38) | DAGLAC5AR1L3MBTL1ESR1TAS2R14 | |
| SCHEMBL11067166 | 0.80 | ESR1 (0.58) | DAGLAC5AR1ESR1TAS2R14RAB9A | |
| SCHEMBL11442725 | 0.77 | S1PR1 (0.44) | DAGLAC5AR1ESR1TAS2R14S1PR1 | |
| SCHEMBL11063373 | 0.77 | CNR2 (0.46) | DAGLAC5AR1ESR1TAS2R14CCR5 | |
| SCHEMBL1137366 | 0.77 | HTR2A (0.39) | ALOX5CYP2C19HTR2AHRH1 | |
| SCHEMBL11060281 | 0.76 | TAS2R14 (0.50) | DAGLAC5AR1ESR1TAS2R14MEN1 | |
| Iodide SCHEMBL9934390 | 0.75 | HTR2A (0.38) | ALOX5CYP2C19HTR2AHRH1 | |
| SCHEMBL3259406 | 0.75 | HTR2A (0.42) | ALOX5CYP2C19MEN1KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL1898617 | 0.75 | TDP1 (0.39) | ALOX5CYP2C19MEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359129-B1 | PROTEASE INHIBITORS | UNIVERSITY OF KANSAS | 2002-03-19 | — | — | US | disclosed |