SCHEMBL11065817

SCHEMBL11065817

Cc1ccc(OP(CCCl)OCCCl)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
DRD2 P14416 2/20 0.33
DRD4 P21917 2/20 0.33
DRD3 P35462 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11064974 0.82 KCNA3 (0.34) TSHRALDH1A1TP53
SCHEMBL25212515 0.70 ACHE (0.41) CYP3A4TSHRACHEDRD2DRD4
SCHEMBL1726956 0.70 ALDH1A1 (0.53) ALDH1A1TP53
SCHEMBL5825048 0.69 DRD2 (0.55) DRD2DRD4DRD3L3MBTL1
Bromide SCHEMBL25222030 0.68 ACHE (0.39) CYP3A4TSHRACHEDRD2DRD4
Hydrochloric Acid SCHEMBL25265433 0.68 ACHE (0.39) CYP3A4TSHRACHEDRD2DRD4
Hydrochloric Acid SCHEMBL25265550 0.67 ACHE (0.42) CYP3A4TSHRACHEDRD2DRD4
Bromide SCHEMBL25197194 0.67 ACHE (0.42) CYP3A4TSHRACHEDRD2DRD4
SCHEMBL11659528 0.67 ACHE (0.38) CYP3A4TSHRACHEDRD2DRD4
SCHEMBL25198215 0.67 ACHE (0.38) CYP3A4TSHRACHEDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4446061-A FIREPROOFING, SMOKELESS, PHOSPHITE/PHOSPHONATE MONSANTO COMPANY (US) 1984-05-01 US disclosed
US-4260542-A FLAME RETARDANTS, SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1981-04-07 US disclosed
US-4206133-A FLAME RETARDANTS AND SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1980-06-03 US disclosed
US-4133823-A FIREPROOFING, SMOKELESS MONSANTO COMPANY (US) 1979-01-09 US disclosed