Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.55 |
| ▸ | CTSB | P07858 | 9/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752532 | 0.96 | CTSL (0.52) | CTSLCTSBTACR1CTSSCTSK | |
| SCHEMBL7594443 | 0.86 | PRSS1 (0.49) | CTSLCTSBCTSS | |
| SCHEMBL25428674 | 0.86 | EPHX2 (0.59) | CTSLCTSBCTSSCTSK | |
| SCHEMBL5394657 | 0.85 | NMBR (0.61) | TACR1ALDH1A1 | |
| SCHEMBL5394660 | 0.85 | NMBR (0.61) | TACR1ALDH1A1 | |
| SCHEMBL9158591 | 0.85 | ITGB3 (0.48) | CTSL | |
| SCHEMBL7327394 | 0.82 | CTSL (0.57) | CTSLCTSBTACR1CTSSCTSK | |
| SCHEMBL10793551 | 0.82 | CTSL (0.57) | CTSLCTSBTACR1CTSSCTSK | |
| SCHEMBL1715348 | 0.82 | CTSL (0.57) | CTSLCTSBTACR1CTSSCTSK | |
| SCHEMBL7326904 | 0.80 | CTSL (0.57) | CTSLCTSBCTSSCTSKCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480030-A | BLOOD-COAGULATION FACTOR XA | PENTAPHARM A.G. (CH) | 1984-10-30 | — | — | US | disclosed |