Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594443 | 0.97 | PRSS1 (0.49) | ITGB3ITGA2BDPP4SIRT2SIRT1 | |
| SCHEMBL11546767 | 0.87 | L3MBTL1 (0.41) | DPP4SIRT2SIRT1SIRT3ECE1 | |
| SCHEMBL11066257 | 0.85 | CTSL (0.55) | CTSL | |
| SCHEMBL16494584 | 0.84 | HDAC1 (0.55) | ITGB3ITGA2BDPP4SIRT2SIRT1 | |
| SCHEMBL648254 | 0.84 | HDAC1 (0.55) | ITGB3ITGA2BDPP4SIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL1930429 | 0.83 | HDAC1 (0.54) | ITGB3ITGA2BDPP4SIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL28627653 | 0.83 | HDAC1 (0.54) | ITGB3ITGA2BDPP4SIRT2SIRT1 | |
| SCHEMBL2778594 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BDPP4SIRT2SIRT1 | |
| SCHEMBL8433172 | 0.82 | HDAC1 (0.65) | ITGB3ITGA2BHDAC1HDAC2CTSL | |
| Hydrochloric Acid SCHEMBL23723888 | 0.82 | HDAC1 (0.56) | ITGB3ITGA2BDPP4SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437563-B1 | BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES | DEBIO RECH PHARMA SA (CH) | 1995-02-22 | — | — | EP | disclosed |
| US-5286637-A | Biologically active drug polymer derivatives and method for preparing same | DEBIOPHARM, S.A. (CH) | 1994-02-15 | — | — | US | disclosed |
| EP-0437563-A1 | BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES. | DEBIOPHARM SA (CH) | 1991-07-24 | — | — | EP | disclosed |
| WO-1991001758-A1 | BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES | DEBIOPHARM S.A. (CH) | 1991-02-21 | — | — | WO | disclosed |