Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061437 | 0.84 | KMT2A (0.58) | KMT2AHSD17B10ACEFFAR2ALDH1A1 | |
| SCHEMBL11066444 | 0.83 | ACE (0.43) | KMT2AHSD17B10NR4A2ACEMAOB | |
| SCHEMBL10938815 | 0.75 | ACE (0.71) | KMT2AACEHTTFFAR2ALDH1A1 | |
| SCHEMBL11066115 | 0.75 | ACE (0.71) | KMT2AACEHTTFFAR2ALDH1A1 | |
| SCHEMBL11067695 | 0.74 | KMT2A (0.53) | KMT2AHSD17B10ACEHTTFFAR2 | |
| SCHEMBL11257852 | 0.74 | ACE (0.55) | KMT2AHSD17B10ACEFFAR2ALDH1A1 | |
| SCHEMBL11110326 | 0.73 | ACE (0.51) | KMT2AACEHTTFFAR2 | |
| SCHEMBL3826252 | 0.72 | POLB (0.51) | HSD17B10HTTFFAR2ALDH1A1 | |
| SCHEMBL3826249 | 0.72 | POLB (0.51) | HSD17B10HTTFFAR2ALDH1A1 | |
| SCHEMBL11385050 | 0.72 | ACE (0.61) | KMT2AHSD17B10ACEFFAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430344-A | Antihypertensive 4-thiazolidinecarboxylic acids | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-02-07 | — | — | US | claimed |