Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066444 | 0.81 | ACE (0.43) | HTTFFAR2HSD17B10KMT2A | |
| SCHEMBL11190505 | 0.80 | HTT (0.39) | HTTFFAR2KMT2A | |
| SCHEMBL11199902 | 0.79 | SMN1; SMN2 (0.42) | HTTFFAR2POLBHSD17B10KMT2A | |
| SCHEMBL11110226 | 0.78 | ACE (0.53) | FFAR2POLBGAARAB9AHSD17B10 | |
| SCHEMBL11186430 | 0.78 | ALDH1A1 (0.44) | FFAR2POLBGAARAB9AHSD17B10 | |
| SCHEMBL11185141 | 0.78 | GAA (0.66) | HTTFFAR2POLBGAARAB9A | |
| SCHEMBL11184570 | 0.77 | POLB (0.47) | FFAR2POLBGAARAB9AHSD17B10 | |
| SCHEMBL11262988 | 0.76 | POLB (0.48) | FFAR2POLBGAARAB9AHSD17B10 | |
| SCHEMBL11190545 | 0.76 | POLB (0.45) | HTTFFAR2POLBGAARAB9A | |
| SCHEMBL11201160 | 0.76 | GAA (0.47) | FFAR2POLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |