Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102355 | 0.83 | KDM4E (0.41) | PTGS2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7167286 | 0.82 | PTGS2 (0.46) | PTGS2KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11067906 | 0.82 | TSHR (0.39) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL5983552 | 0.79 | PTGS2 (0.46) | PTGS2MAPTKDM4EPOLBHTT | |
| SCHEMBL5112475 | 0.79 | PTGS2 (0.46) | PTGS2MAPTKDM4EPOLBHTT | |
| SCHEMBL30222272 | 0.79 | PTGS2 (0.46) | PTGS2MAPTKDM4EPOLBHTT | |
| SCHEMBL27081480 | 0.79 | XPO1 (0.40) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL7822153 | 0.78 | PTGS2 (0.44) | PTGS2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL1063487 | 0.78 | PTGS2 (0.44) | PTGS2MAPTKDM4EKMT2ACYP2C9 | |
| SCHEMBL3026634 | 0.76 | PTGS2 (0.43) | PTGS2MAPTKDM4EKMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074008-B1 | PROCESS FOR PRODUCING ALPHA-ARYLALKANOIC ACID ESTERS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4433160-A | Process for producing α-arylalkanoic acid ester | TAISHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| US-4420631-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-12-13 | — | — | US | disclosed |
| EP-0074008-A2 | Process for producing alpha-arylalkanoic acid esters | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-03-16 | — | — | EP | disclosed |