Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098859 | 0.87 | ADRA2C (0.41) | PTGS2ADRA2CADRA2AADRA2BCYP2C19 | |
| SCHEMBL5683696 | 0.86 | PTGS2 (0.46) | PTGS2MMP1MMP2MMP9MMP8 | |
| SCHEMBL20921258 | 0.83 | ADRA2C (0.43) | PTGS2ADRA2CADRA2AADRA2BPTGS1 | |
| Hydrogen Peroxide SCHEMBL27481344 | 0.82 | ADRA2C (0.47) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL11066693 | 0.82 | PTGS2 (0.42) | PTGS2MMP1MMP2MMP9MMP8 | |
| SCHEMBL7691515 | 0.81 | LMNA (0.42) | ADRA2CADRA2AADRA2BCYP2C19GABRA1 | |
| SCHEMBL9748533 | 0.81 | CYP2C19 (0.46) | PTGS2ADRA2CADRA2AADRA2BCYP2C19 | |
| SCHEMBL5983552 | 0.80 | PTGS2 (0.46) | PTGS2MMP1MMP2MMP9MMP8 | |
| SCHEMBL30222272 | 0.80 | PTGS2 (0.46) | PTGS2MMP1MMP2MMP9MMP8 | |
| SCHEMBL5112475 | 0.80 | PTGS2 (0.46) | PTGS2MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441979-B1 | OPTICALLY ACTIVE 2-(ALKYL-SUBSTITUTED PHENYL)-PROPIONIC ACID DERIVATIVE AND OPTICAL RESOLUTION OF ( )-1-METHYL-3-PHENYLPROPYLAMINE | DAICEL CHEM (JP) | 1996-01-31 | — | — | EP | claimed |
| EP-0441979-A1 | OPTICALLY ACTIVE 2-(ALKYL-SUBSTITUTED PHENYL)-PROPIONIC ACID DERIVATIVE AND OPTICAL RESOLUTION OF ( )-1-METHYL-3-PHENYLPROPYLAMINE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | claimed |
| EP-0240665-B1 | PROCESS FOR REFINING 2-(ARYL SUBSTITUTED) PROPIONIC ACID OR ITS SALTS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-05-29 | — | — | EP | claimed |
| EP-0232863-B1 | PROCESS FOR PRODUCING AN (ARYL SUBSTITUTED) CARBOXYLIC ACID OR ITS SALT | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | claimed |
| US-4814494-A | OXIDATION, HYDROGENATION | NIPPON PETROCHEMICALS COMPANY, LTD. (JP) | 1989-03-21 | — | — | US | claimed |
| US-4709089-A | DEHALOGENATION | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | claimed |
| EP-0240665-A1 | Process for refining 2-(aryl substituted) propionic acid or its salts | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | claimed |
| EP-0232863-A1 | Process for producing an (aryl substituted) carboxylic acid or its salt | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-08-19 | — | — | EP | claimed |
| US-20030143701-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. | 2003-07-31 | — | — | US | disclosed |
| EP-0924194-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6528686-B1 | Reacting primary amine and ketone functionalized derivatives; catalytically reducing | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0939134-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0924194-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5629200-A | MICROORGANISM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0441979-B1 | OPTICALLY ACTIVE 2-(ALKYL-SUBSTITUTED PHENYL)-PROPIONIC ACID DERIVATIVE AND OPTICAL RESOLUTION OF ( )-1-METHYL-3-PHENYLPROPYLAMINE | DAICEL CHEM (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0654534-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0441979-A1 | OPTICALLY ACTIVE 2-(ALKYL-SUBSTITUTED PHENYL)-PROPIONIC ACID DERIVATIVE AND OPTICAL RESOLUTION OF ( )-1-METHYL-3-PHENYLPROPYLAMINE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |