Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102355 | 0.87 | KDM4E (0.41) | SMN1; SMN2KMT2AALDH1A1MEN1BTN3A1 | |
| SCHEMBL28008699 | 0.83 | TSHR (0.46) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL11066693 | 0.82 | PTGS2 (0.42) | LMNASMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL7628102 | 0.80 | TSHR (0.43) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL7625054 | 0.79 | TSHR (0.43) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL15253448 | 0.79 | TSHR (0.43) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL28008700 | 0.77 | CYSLTR2 (0.47) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL363983 | 0.76 | TSHR (0.48) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL28008252 | 0.75 | NLRP3 (0.50) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL27081480 | 0.74 | XPO1 (0.40) | SMN1; SMN2KMT2AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074008-B1 | PROCESS FOR PRODUCING ALPHA-ARYLALKANOIC ACID ESTERS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4433160-A | Process for producing α-arylalkanoic acid ester | TAISHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| EP-0074008-A2 | Process for producing alpha-arylalkanoic acid esters | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-03-16 | — | — | EP | disclosed |