Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | GAA | P10253 | 8/20 | 0.40 |
| ▸ | GLA | P06280 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071978 | 0.84 | GAA (0.54) | LMNAHTTKDM4EGAAGLA | |
| SCHEMBL10509864 | 0.83 | PDE5A (0.39) | KDM4EKMT2AHSD17B10HPGDMAPT | |
| SCHEMBL11066769 | 0.82 | ABCB11 (0.49) | KDM4EGAAGLAKMT2AHSD17B10 | |
| SCHEMBL11071263 | 0.82 | KDM4E (0.41) | LMNAHTTKDM4EGAAGLA | |
| SCHEMBL10510661 | 0.81 | PDE5A (0.35) | KMT2AHPGDMAPTMEN1 | |
| SCHEMBL10506675 | 0.80 | PDE5A (0.36) | KDM4EGAAGLAKMT2AHSD17B10 | |
| SCHEMBL10505460 | 0.77 | TNKS (0.45) | KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL9204366 | 0.76 | PDE5A (0.33) | KMT2AHPGDMAPTMEN1 | |
| SCHEMBL10507162 | 0.75 | PDE5A (0.35) | KMT2AHPGDMAPTMEN1TSHR | |
| SCHEMBL10506342 | 0.75 | PDE5A (0.35) | KMT2AHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |