Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066772 | 0.84 | LMNA (0.41) | GAAKDM4EGLAMCL1LMNA | |
| SCHEMBL11071974 | 0.83 | KDM4E (0.57) | GAAKDM4EGLACA9MCL1 | |
| SCHEMBL11081738 | 0.83 | KDM4E (0.49) | GAAKDM4EGLACA9LMNA | |
| SCHEMBL11077944 | 0.72 | KDM4E (0.52) | GAAKDM4EGLACA9MCL1 | |
| SCHEMBL11384270 | 0.71 | SRD5A1 (0.67) | GAAKDM4EGLACA9SRD5A1 | |
| SCHEMBL11071263 | 0.71 | KDM4E (0.41) | GAAKDM4EGLAMCL1LMNA | |
| SCHEMBL11075633 | 0.71 | KDM4E (0.70) | GAAKDM4EGLACA9MCL1 | |
| SCHEMBL3878331 | 0.70 | CA9 (0.65) | GAAKDM4EGLACA9SRD5A1 | |
| SCHEMBL11098613 | 0.69 | KDM4E (0.50) | GAAKDM4EGLAMCL1LMNA | |
| SCHEMBL7824982 | 0.68 | LMNA (0.62) | GAAKDM4EGLASRD5A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |