Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410945 | 0.79 | TSHR (0.48) | TSHRAKR1B1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4576468 | 0.77 | SLC22A12 (0.50) | SLC22A12CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL31410946 | 0.77 | TSHR (0.50) | TSHRAKR1B1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL18301791 | 0.76 | SLC22A12 (0.43) | TSHRSLC22A12PTGS2CA2 | |
| SCHEMBL22918241 | 0.74 | AKR1B1 (0.38) | AKR1B1SLC22A12PTGS2CXCL8CA2 | |
| SCHEMBL4837065 | 0.72 | AKR1B1 (0.45) | AKR1B1FABP4FABP5CYP2C9PTGS2 | |
| SCHEMBL12367132 | 0.71 | ALOX15 (0.50) | TSHRCYP2C9CYP1A2CYP2C19CA2 | |
| SCHEMBL3325379 | 0.71 | ALOX15 (0.47) | TSHRAKR1B1PTGS2CXCL8CA2 | |
| SCHEMBL11530256 | 0.70 | PGK1 (0.35) | AKR1B1CYP2C9PTGS2CXCL8CA2 | |
| SCHEMBL20276014 | 0.69 | TSHR (0.62) | TSHRCYP2C9CYP1A2CYP2C19ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455298-A | MOLLUSC EXTRACT | MCFARLANE STUART J (NZ) | 1984-06-19 | — | — | US | disclosed |
| EP-0010061-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING A MOLLUSC EXTRACT | Mc Farlane, Stuart John (NZ) | 1983-07-13 | — | — | EP | disclosed |
| WO-1980000661-A1 | PHARMACEUTICAL PREPARATIONS | CROFT J (NZ) | 1980-04-17 | — | — | WO | disclosed |
| EP-0010061-A1 | Pharmaceutical preparations containing a mollusc extract | Mc Farlane, Stuart John (NZ) | 1980-04-16 | — | — | EP | disclosed |