Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529743 | 0.86 | PGK1 (0.36) | PGK1PTGS2AKR1B1CXCL8CA2 | |
| SCHEMBL11531086 | 0.81 | NPSR1 (0.39) | PTGS2AKR1B1PTGS1 | |
| SCHEMBL11529131 | 0.74 | PGK1 (0.36) | PGK1PTGS2AKR1B1CXCL8CA2 | |
| Methane SCHEMBL11527961 | 0.73 | PGK1 (0.36) | PGK1PTGS2AKR1B1CXCL8CA2 | |
| Methyl Alcohol SCHEMBL11530669 | 0.73 | PGK1 (0.36) | PGK1PTGS2AKR1B1CXCL8CA2 | |
| SCHEMBL4837065 | 0.72 | AKR1B1 (0.45) | PTGS2AKR1B1CXCL8CA2CAMK2A | |
| SCHEMBL3325379 | 0.71 | ALOX15 (0.47) | PTGS2AKR1B1CXCL8CA2PTGS1 | |
| SCHEMBL11066945 | 0.70 | TSHR (0.42) | PTGS2AKR1B1CXCL8CA2CYP2C9 | |
| SCHEMBL11532270 | 0.70 | PGK1 (0.40) | PGK1 | |
| SCHEMBL5861443 | 0.70 | AHR (0.45) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | claimed |
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |