SCHEMBL4837065

SCHEMBL4837065

O=C(O)Cc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.45
CA2 P00918 1/20 0.44
CXCL8 P10145 4/20 0.43
CAMK2A Q9UQM7 5/20 0.41
CYP2C9 P11712 1/20 0.41
CHRM1 P11229 1/20 0.41
PTGS2 P35354 2/20 0.41
AKR1B10 O60218 1/20 0.41
UGT1A9 O60656 1/20 0.41
TRPA1 O75762 1/20 0.41
ABCB11 O95342 1/20 0.41
MT-CO2 P00403 1/20 0.41
TTR P02766 1/20 0.41
ALB P02768 1/20 0.41
UGT1A6 P19224 1/20 0.41
UGT1A1 P22309 1/20 0.41
PTGS1 P23219 1/20 0.41
CXCR1 P25024 1/20 0.41
ADRA1A P35348 1/20 0.41
AGTR2 P50052 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14793743 0.85 CA2 (0.53) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL9755274 0.85 CA2 (0.53) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL17466155 0.83 NPSR1 (0.44) AKR1B1CA2CXCL8PTGS2
SCHEMBL7164323 0.83 ABCB11 (0.40) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL3329203 0.83 P2RX7 (0.40) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL11076027 0.83 THRB (0.40) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL3580327 0.83 GAA (0.48) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL11164004 0.82 CA2 (0.50) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL21352167 0.80 AKR1B1 (0.41) AKR1B1CA2CXCL8CAMK2ACYP2C9
SCHEMBL3325379 0.80 ALOX15 (0.47) AKR1B1CA2CXCL8PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442549-B2 Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid SAPPORO BREWERIES LIMITED (JP) 2008-10-28 US claimed
US-20050289663-A1 Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid SAPPORO BREWERIES LIMITED (JP) 2005-12-29 US claimed
EP-1541015-A1 METHOD OF CONSTRUCTING ORCHID HAPLOID BY TREATING UNFERTILIZED OCRHID FLOWER WITH AUXIN AND METHOD OF GROWING ORCHID Sapporo Breweries Limited (JP) 2005-06-15 EP claimed
EP-0710648-B1 Method for producing oxyindoles KI CHEMICAL INDUSTRY CO LTD (JP) 2002-04-03 EP claimed
US-5679799-A Method for producing oxyindoles K-I CHEMICAL INDUSTRY CO., LTD. (JP) 1997-10-21 US claimed
EP-0710648-A1 Method for producing oxyindoles K I CHEMICAL INDUSTRY CO., LTD. (JP) 1996-05-08 EP claimed
US-7442549-B2 Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid SAPPORO BREWERIES LIMITED (JP) 2008-10-28 US disclosed
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-20050289663-A1 Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid SAPPORO BREWERIES LIMITED (JP) 2005-12-29 US disclosed
US-6933261-B2 2,4,5-Trisubstituted phenylketoenols BAYER AKTIENGESELLSCHAFT (DE) 2005-08-23 US disclosed
EP-1541015-A1 METHOD OF CONSTRUCTING ORCHID HAPLOID BY TREATING UNFERTILIZED OCRHID FLOWER WITH AUXIN AND METHOD OF GROWING ORCHID Sapporo Breweries Limited (JP) 2005-06-15 EP disclosed
US-5679799-A Method for producing oxyindoles K-I CHEMICAL INDUSTRY CO., LTD. (JP) 1997-10-21 US disclosed
WO-1997001535-A1 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed
EP-0710648-A1 Method for producing oxyindoles K I CHEMICAL INDUSTRY CO., LTD. (JP) 1996-05-08 EP disclosed
US-5100800-A Pseudomonas for degradation of chlorobenzoic acids, pollution control HON GROUP, THE 1992-03-31 US disclosed
EP-0023332-A2 Fungicidal thioglycolic acid anilides, process for their preparation and pesticides containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-04 EP disclosed
US-4022610-A Herbicidal mixed salts of magnesium VELSICOL CHEMICAL CORPORATION (US) 1977-05-10 US disclosed
US-3957891-A HERBICIDES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-05-18 US disclosed