Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066992 | 0.85 | ABCB1 (0.56) | OPRL1POLB | |
| SCHEMBL11065111 | 0.85 | SIGMAR1 (0.53) | SIGMAR1CCR3 | |
| SCHEMBL10575317 | 0.82 | SIGMAR1 (0.54) | HTR6SIGMAR1 | |
| SCHEMBL11072709 | 0.82 | MEN1 (0.47) | OPRL1SIGMAR1 | |
| SCHEMBL10568199 | 0.78 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL11069074 | 0.77 | HTR7 (0.46) | OPRL1SIGMAR1 | |
| SCHEMBL11062798 | 0.77 | CHRM2 (0.60) | HTR6 | |
| SCHEMBL11070274 | 0.76 | CHRM1 (0.55) | HTR6SIGMAR1 | |
| SCHEMBL10572966 | 0.76 | DRD2 (0.52) | SIGMAR1 | |
| SCHEMBL11729211 | 0.74 | HTR6 (0.48) | HTR6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |