SCHEMBL11067601

SCHEMBL11067601

CCCCc1ccc[c]c1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.35
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TYR P14679 1/20 0.33
ALOX5 P09917 1/20 0.32
PTGS2 P35354 1/20 0.32
KCNH2 Q12809 6/20 0.31
TLR8 Q9NR97 1/20 0.31
FAAH O00519 1/20 0.31
BID P55957 1/20 0.30
BCL2L1 Q07817 1/20 0.30
MCL1 Q07820 1/20 0.30
BAK1 Q16611 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3464470 0.95 LIPG (0.41) LIPGALOX5PTGS2KCNH2FAAH
SCHEMBL2059825 0.93 LIPG (0.44) LIPGKCNH2FAAHBIDBCL2L1
SCHEMBL10732727 0.93 LIPG (0.44) LIPGKCNH2FAAHBIDBCL2L1
SCHEMBL5311184 0.93 LIPG (0.44) LIPGKCNH2FAAHBIDBCL2L1
SCHEMBL16951213 0.89 AR (0.33)
SCHEMBL7401991 0.82 GABRA1 (0.40) CYP2D6
SCHEMBL27944348 0.79 ALDH1A1 (0.31)
SCHEMBL27584943 0.79 TDP1 (0.30)
SCHEMBL7082402 0.79 TRPV1 (0.32)
SCHEMBL919936 0.77 TYR (0.39) LIPGCYP3A4CYP2D6CYP2C9TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4474965-A PLANT GROWTH AGENTS MONSANTO COMPANY (US) 1984-10-02 US disclosed
US-4371388-A 3-Substituted aminoalkyl-2-benzothiazolinones as plant growth regulants MONSANTO COMPANY (US) 1983-02-01 US disclosed