Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17046318 | 0.85 | PDK2 (0.33) | — | |
| SCHEMBL27944348 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL27584943 | 0.81 | TDP1 (0.30) | TDP1 | |
| SCHEMBL16951213 | 0.81 | AR (0.33) | — | |
| SCHEMBL11067601 | 0.79 | LIPG (0.35) | — | |
| SCHEMBL3464470 | 0.77 | LIPG (0.41) | — | |
| SCHEMBL27937767 | 0.77 | — | — | |
| SCHEMBL7401991 | 0.77 | GABRA1 (0.40) | — | |
| SCHEMBL27899133 | 0.77 | PNMT (0.34) | — | |
| SCHEMBL5311184 | 0.76 | LIPG (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347864-A | For treating diseases caused by Lp-PLA2Pyrimidone compounds for mediated diseases or conditions | GLAXO GROUP LTD | 2013-10-09 | — | — | CN | disclosed |
| EP-1280784-A2 | BIOLOGICALLY ACTIVE 4H-BENZO 1,4]OXAZIN-3-ONES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001087862-A2 | BIOLOGICALLY ACTIVE 4H-BENZO[1,4]OXAZIN-3-ONES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-22 | — | — | WO | disclosed |