Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL28577416 | 0.89 | GPR35 (0.69) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| Trinitrophenol SCHEMBL20695024 | 0.87 | GPR35 (0.67) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| Trinitrophenol SCHEMBL29086892 | 0.85 | GPR35 (0.74) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| Trinitrophenol SCHEMBL253750 | 0.84 | GPR35 (0.79) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| Trinitrophenol SCHEMBL8744 | 0.84 | GPR35 (0.79) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| 3,5-Dinitrosalicylic Acid SCHEMBL28322215 | 0.84 | GPR35 (0.59) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| 3,5-Dinitrosalicylic Acid SCHEMBL29350581 | 0.84 | ALDH1A1 (0.61) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| Trinitrophenol SCHEMBL29391747 | 0.84 | GPR35 (0.62) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| 3,5-Dinitrosalicylic Acid SCHEMBL125292 | 0.84 | ALDH1A1 (0.61) | GPR35ALDH1A1KMT2AMEN1HPGD | |
| 3,5-Dinitrosalicylic Acid SCHEMBL28323234 | 0.84 | ALDH1A1 (0.61) | GPR35ALDH1A1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355726-A1 | NEW TYPE OF CYTIDINE DERIVATIVE AND APPLICATION THEREOF | CHANGZHOU FANGYUAN PHARMACEUTICAL CO., LTD (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20130153098-A1 | Gas Generant Compositions | JOYSON SAFETY SYSTEMS ACQUISITION LLC | 2013-06-20 | — | — | US | disclosed |
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355726-A1 | NEW TYPE OF CYTIDINE DERIVATIVE AND APPLICATION THEREOF | DCTD, RNMT, TYMP | GPR35 3275/4885ALDH1A1 1450/4885KMT2A 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.