Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068861 | 0.86 | GABRA1 (0.42) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL11065152 | 0.84 | HSP90AB1 (0.41) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL11070696 | 0.81 | TSHR (0.47) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL11563189 | 0.79 | HMGB1 (0.50) | HSD17B1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL23399275 | 0.79 | HMGB1 (0.55) | HSD17B1GAAKDM4EMAPTTSHR | |
| SCHEMBL11289196 | 0.78 | MEN1 (0.45) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL7756384 | 0.78 | PTPN1 (0.53) | HSD17B1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL11288742 | 0.77 | PTGS2 (0.49) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL14458139 | 0.76 | MEN1 (0.48) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL20670595 | 0.76 | ALDH1A1 (0.54) | HSD17B1ALDH1A1GAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |