Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291358 | 0.90 | MAPK1 (0.45) | MEN1KMT2AALDH1A1CNR1CNR2 | |
| SCHEMBL11288742 | 0.89 | PTGS2 (0.49) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11296771 | 0.88 | MAPT (0.46) | MEN1KMT2APLK1ALDH1A1CNR1 | |
| SCHEMBL11296456 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2APLK1ALDH1A1CNR1 | |
| SCHEMBL11311902 | 0.87 | CNR2 (0.53) | MEN1KMT2APLK1ALDH1A1CNR1 | |
| SCHEMBL11296742 | 0.84 | TDP1 (0.43) | MEN1KMT2APLK1ALDH1A1CNR1 | |
| SCHEMBL51624 | 0.82 | PLK1 (0.49) | MEN1KMT2APLK1ALDH1A1CNR1 | |
| SCHEMBL11067893 | 0.78 | HSD17B1 (0.41) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11065152 | 0.77 | HSP90AB1 (0.41) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL10370243 | 0.76 | MAPT (0.65) | PLK1ALDH1A1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |