SCHEMBL11068046

SCHEMBL11068046

Brc1ccc(Oc2ccc(Br)c3ccccc23)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 1/20 0.47
GPR84 Q9NQS5 1/20 0.41
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RXFP1 Q9HBX9 1/20 0.38
HTR6 P50406 1/20 0.37
IDO1 P14902 1/20 0.35
TSHR P16473 1/20 0.35
AAK1 Q2M2I8 1/20 0.35
EP300 Q09472 1/20 0.34
KAT8 Q9H7Z6 1/20 0.34
NQO2 P16083 1/20 0.34
PRNP P04156 1/20 0.33
CYP1A2 P05177 1/20 0.33
PARP1 P09874 1/20 0.33
ESRRA P11474 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24871110 0.83 SLC6A4 (0.44) PKML3MBTL1LMNAGPR84MAPK1
SCHEMBL30719614 0.81 IDO1 (0.57) PKML3MBTL1LMNAMAPK1ALDH1A1
SCHEMBL1891196 0.81 IDO1 (0.57) PKML3MBTL1LMNAMAPK1ALDH1A1
SCHEMBL198796 0.81 RXFP1 (0.48) PKML3MBTL1LMNAALDH1A1TDP1
SCHEMBL29429114 0.81 RXFP1 (0.48) PKML3MBTL1LMNAALDH1A1TDP1
SCHEMBL30710586 0.81 RXFP1 (0.48) PKML3MBTL1LMNAALDH1A1TDP1
SCHEMBL25056747 0.80 PKM (0.45) PKML3MBTL1LMNAMAPK1ALDH1A1
SCHEMBL16668583 0.79 PKM (0.47) PKML3MBTL1LMNAGPR84RXFP1
SCHEMBL7527797 0.79 IDO1 (0.55) PKML3MBTL1LMNAMAPK1ALDH1A1
SCHEMBL15449549 0.76 PKM (0.49) PKML3MBTL1LMNAGPR84ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4289839-A BLOCKED COUPLER LIBERATED BY PHOTOCHEMICALLY FORMED ACID JAMES RIVER GRAPHICS, INC. (US) 1981-09-15 US claimed
US-4482489-A USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS JAMES RIVER GRAPHICS, INC. (US) 1984-11-13 US disclosed
US-4289839-A BLOCKED COUPLER LIBERATED BY PHOTOCHEMICALLY FORMED ACID JAMES RIVER GRAPHICS, INC. (US) 1981-09-15 US disclosed