Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | EP300 | Q09472 | 2/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.52 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719614 | 1.00 | IDO1 (0.57) | IDO1EP300KAT8PKMIMPDH2 | |
| SCHEMBL7527797 | 0.98 | IDO1 (0.55) | IDO1EP300KAT8PKMIMPDH2 | |
| SCHEMBL5759879 | 0.86 | IDO1 (0.47) | IDO1EP300KAT8PKMIMPDH2 | |
| SCHEMBL29380721 | 0.85 | IDO1 (0.73) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL419307 | 0.85 | IDO1 (0.73) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL28007983 | 0.83 | IDO1 (0.44) | IDO1EP300KAT8PKMIMPDH2 | |
| SCHEMBL11068046 | 0.81 | PKM (0.52) | IDO1EP300KAT8PKMLMNA | |
| SCHEMBL9611883 | 0.79 | APP (0.46) | PKMLMNAL3MBTL1HPGDKMT2A | |
| SCHEMBL12019841 | 0.78 | IDO1 (0.64) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL7753164 | 0.78 | IDO1 (0.64) | IDO1EP300KAT8IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024365-B | Industrial production method of benzo [ c ] phenanthrene-5-trifluoromethanesulfonate | 西安瑞联新材料股份有限公司 | 2023-02-10 | — | — | CN | claimed |
| CN-113024365-A | Industrial production method of benzo [ c ] phenanthrene-5-trifluoromethanesulfonate | 西安瑞联新材料股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-113801087-B | Benzo-six-membered ring derivatives as DPP-4 inhibitors and uses thereof | 山东百极地长制药有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118530189-A | Naphthalene-substituted condensed aromatic ring type organic compound, application thereof and organic electroluminescent device | 北京鼎材科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118307518-A | Polycyclic PARP selective inhibitors | 轩竹生物科技股份有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-20240158427-A1 | RED-LIGHT IRIDIUM COMPLEX AND USE THEREOF | PHICHEM CORPORATION (CN) | 2024-05-16 | — | — | US | disclosed |
| CN-113801088-B | Benzo six-membered ring derivative and application thereof | 山东百极地长制药有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117659025-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-03-08 | — | — | CN | disclosed |
| CN-117586108-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586191-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | SRX CARDIO, LLC (US) | 2024-02-06 | — | — | US | disclosed |
| CN-1329615-A | Hydroboronation process | COMMW SCIENT IND RES ORG (AU) | 2002-01-02 | — | — | CN | disclosed |
| EP-1127060-A1 | HYDROBORONATION PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2001-08-29 | — | — | EP | disclosed |
| CN-1261276-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2000-07-26 | — | — | CN | disclosed |
| WO-2000027853-A1 | HYDROBORONATION PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-05-18 | — | — | WO | disclosed |
| EP-0980386-A2 | ESTROGEN RECEPTOR CRYSTALS AND LIGANDS | KARO BIO AB (SE) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998056812-A2 | ESTROGEN RECEPTOR CRYSTALS AND LIGANDS | KARO BIO AB (SE) | 1998-12-17 | — | — | WO | disclosed |
| WO-1997015566-A1 | NOVEL OLIGOMERS, PROCESS FOR THEIR PREPARATION AND METHODS FOR THEIR USE | GEORGHIOU PARIS E (CA) | 1997-05-01 | — | — | WO | disclosed |
| US-4042635-A | Spiro compounds | CIBA-GEIGY CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-3950403-A | Spiro compounds | CIBA-GEIGY CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | PCSK9, PCSK6, PCSK7 | IDO1 3730/4885EP300 2232/4885KAT8 2135/4885 |
| US-20240158427-A1 | RED-LIGHT IRIDIUM COMPLEX AND USE THEREOF | IK, F10, DRD3 | IDO1 143/4885EP300 2646/4885KAT8 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.