Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15449549 | 0.83 | PKM (0.49) | PKMLMNAL3MBTL1GPR84RXFP1 | |
| SCHEMBL11068046 | 0.79 | PKM (0.52) | PKMLMNAL3MBTL1GPR84RXFP1 | |
| SCHEMBL30719614 | 0.76 | IDO1 (0.57) | PKMLMNAL3MBTL1IDO1NQO2 | |
| SCHEMBL1891196 | 0.76 | IDO1 (0.57) | PKMLMNAL3MBTL1IDO1NQO2 | |
| SCHEMBL30710586 | 0.75 | RXFP1 (0.48) | PKMLMNAL3MBTL1RXFP1HTR6 | |
| SCHEMBL198796 | 0.75 | RXFP1 (0.48) | PKMLMNAL3MBTL1RXFP1HTR6 | |
| SCHEMBL29429114 | 0.75 | RXFP1 (0.48) | PKMLMNAL3MBTL1RXFP1HTR6 | |
| SCHEMBL15901381 | 0.74 | GPR84 (0.39) | GPR84IDO1EP300KAT8NQO1 | |
| SCHEMBL904667 | 0.74 | CYP1A2 (0.56) | LMNAL3MBTL1IDO1EP300KAT8 | |
| SCHEMBL7527797 | 0.74 | IDO1 (0.55) | PKMLMNAL3MBTL1IDO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127261-A1 | COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG | 天津济坤医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |
| CN-112574216-B | Compound, preparation method thereof and application thereof in preparing anti-cancer drugs | 天津济坤医药科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-112574216-A | Compound, preparation method thereof and application thereof in preparing anti-cancer drugs | 天津济坤医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |
| US-9601699-B2 | Chrysene-based compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-03-21 | — | — | US | disclosed |
| US-20150115232-A1 | CHRYSENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-04-30 | — | — | US | disclosed |