Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066226 | 0.90 | DRD4 (0.62) | DRD4 | |
| SCHEMBL11063819 | 0.90 | CHRM2 (0.46) | DRD4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10568516 | 0.86 | HTR7 (0.50) | — | |
| SCHEMBL10569797 | 0.85 | GAA (0.47) | — | |
| SCHEMBL11071115 | 0.84 | ADRB2 (0.63) | DRD4ADRB2CHRM2CHRM4ADRB1 | |
| SCHEMBL11069003 | 0.81 | DRD4 (0.62) | DRD4DRD2 | |
| SCHEMBL11071590 | 0.80 | MAOA (0.69) | DRD4DRD2 | |
| SCHEMBL11065731 | 0.80 | DRD4 (0.58) | DRD4ADRB2CHRM2CHRM4ADRB1 | |
| SCHEMBL10568734 | 0.80 | MEN1 (0.48) | — | |
| SCHEMBL11068145 | 0.80 | KCNH2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |