Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.78 |
| ▸ | LTA4H | P09960 | 11/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066953 | 0.89 | OPRK1 (0.63) | OPRK1LTA4HPPARAPPARGMMP8 | |
| SCHEMBL11358611 | 0.88 | OPRK1 (0.63) | OPRK1PPARAPPARGMMP8ABCB11 | |
| Beclobrate SCHEMBL3950803 | 0.88 | OPRK1 (1.00) | OPRK1PPARAPPARGABCB11CYP1A2 | |
| Beclobrate SCHEMBL49779 | 0.88 | OPRK1 (1.00) | OPRK1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL5660644 | 0.86 | OPRK1 (0.60) | OPRK1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL11459021 | 0.83 | OPRK1 (0.54) | OPRK1LTA4HPPARAPPARGELANE | |
| SCHEMBL22238907 | 0.82 | OPRK1 (0.68) | OPRK1PPARAPPARGABCB11CYP1A2 | |
| SCHEMBL4874274 | 0.81 | OPRK1 (0.66) | OPRK1LTA4HPPARAPPARGABCB11 | |
| SCHEMBL14584556 | 0.80 | OPRK1 (0.56) | OPRK1PPARAPPARG | |
| SCHEMBL14584527 | 0.80 | OPRK1 (0.56) | OPRK1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483999-A | Phenoxy alkanoic acid derivatives having the ability to lower the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-11-20 | — | — | US | claimed |