Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 13/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065117 | 0.79 | BTK (0.45) | HPGDSPROKR1MTNR1AMTNR1BBTK | |
| SCHEMBL9671400 | 0.73 | RBP4 (0.48) | HPGDSPROKR1 | |
| SCHEMBL16446718 | 0.72 | PROKR1 (0.54) | HPGDSPROKR1 | |
| SCHEMBL9671327 | 0.69 | HPGDS (0.44) | HPGDSPROKR1 | |
| SCHEMBL5770265 | 0.68 | RBP4 (0.47) | HPGDSPROKR1 | |
| SCHEMBL2280008 | 0.67 | RBP4 (0.50) | HPGDS | |
| SCHEMBL2273751 | 0.65 | RBP4 (0.51) | HPGDS | |
| SCHEMBL10491659 | 0.65 | PROKR1 (0.47) | HPGDSPROKR1 | |
| SCHEMBL5768898 | 0.65 | PROKR1 (0.46) | PROKR1 | |
| SCHEMBL10491646 | 0.65 | PROKR1 (0.44) | HPGDSPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435408-A | Dopaminergic stimulating and antianoxic 4-substituted 2H-indole-2-ones | ROUSSEL UCLAF (FR) | 1984-03-06 | — | — | US | disclosed |