Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724290 | 0.90 | ABCB1 (0.41) | ABCB1ADRB2ADRB1ADRB3LOXL2 | |
| SCHEMBL10572085 | 0.81 | MAPT (0.59) | ABCB1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL11064919 | 0.79 | ADRB2 (0.51) | ABCB1ADRB2ADRB1ADRB3 | |
| SCHEMBL11066890 | 0.78 | ABCB1 (0.57) | ABCB1ADRB2ADRB1ADRB3LMNA | |
| Oxalic Acid SCHEMBL11068715 | 0.77 | KCNH2 (0.50) | ABCB1ADRB2ADRB1ADRB3 | |
| Iodide SCHEMBL11071830 | 0.77 | SLC18A3 (0.44) | ABCB1ADRB2ADRB1ADRB3LOXL2 | |
| Oxalic Acid SCHEMBL11064628 | 0.76 | ABCB1 (0.57) | ABCB1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL11062978 | 0.76 | ADRB2 (0.46) | ABCB1ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL11726085 | 0.76 | CYP1A2 (0.45) | ABCB1ADRB2ADRB1ADRB3LOXL2 | |
| SCHEMBL11062792 | 0.76 | ALDH1A1 (0.40) | LOXL2SIGMAR1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |