Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | TCF4 | P15884 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002271 | 0.79 | KDM4E (0.42) | KDM4ELMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL3323373 | 0.77 | LMNA (0.40) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL6560166 | 0.77 | SMN1; SMN2 (0.39) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL3885913 | 0.75 | CHAT (0.46) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL30278762 | 0.75 | CHAT (0.46) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL11209473 | 0.75 | LMNA (0.38) | KDM4ELMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL5716038 | 0.73 | SMN1; SMN2 (0.41) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL6554236 | 0.72 | RAB9A (0.45) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL6559486 | 0.72 | SMN1; SMN2 (0.39) | KDM4ELMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL38661525 | 0.71 | KMT2A (0.40) | MEN1KMT2AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431774-A | QUINOLINIUM SULFONATES AS LATENT ACID CATALYSTS; RADIATION; DECOMPOSITION; STORAGE STABILITY | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |