Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885913 | 1.00 | CHAT (0.46) | CHATKDM4EUBE2NSMN1; SMN2HTT | |
| SCHEMBL5716038 | 0.94 | SMN1; SMN2 (0.41) | CHATKDM4EUBE2NSMN1; SMN2HTT | |
| SCHEMBL22444491 | 0.88 | HTT (0.45) | CHATKDM4EUBE2NSMN1; SMN2HTT | |
| SCHEMBL4609887 | 0.86 | CHAT (0.53) | CHATKDM4EUBE2NSMN1; SMN2HTT | |
| SCHEMBL1002271 | 0.83 | KDM4E (0.42) | CHATKDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL29357465 | 0.83 | CHAT (0.62) | CHATKDM4ESMN1; SMN2HTTNPSR1 | |
| SCHEMBL876926 | 0.83 | CHAT (0.62) | CHATKDM4ESMN1; SMN2HTTNPSR1 | |
| SCHEMBL6554349 | 0.82 | CHAT (0.49) | CHATKDM4ESMN1; SMN2HTTNPSR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7049988 | 0.81 | HTT (0.48) | CHATKDM4ESMN1; SMN2HTTNPSR1 | |
| SCHEMBL3323373 | 0.81 | LMNA (0.40) | CHATKDM4ESMN1; SMN2HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026104266-A1 | USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2026-05-21 | — | — | WO | claimed |
| EP-4739272-A1 | OXIDATIVE HAIR COLOURING COMPOSITION | Wella Germany GmbH (DE) | 2026-05-13 | — | — | EP | claimed |
| EP-4731170-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | Wella Germany GmbH (DE) | 2026-04-29 | — | — | EP | claimed |
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | WELLA GERMANY GMBH (DE) | 2026-03-03 | — | — | US | claimed |
| EP-3873407-B1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | HENKEL AG & CO KGAA (DE) | 2025-04-09 | — | — | EP | claimed |
| WO-2025031867-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | WELLA GERMANY GMBH (DE) | 2025-02-13 | — | — | WO | claimed |
| WO-2025008339-A1 | OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2025-01-09 | — | — | WO | claimed |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | claimed |
| WO-2023017039-A1 | HAIR COLORING COMPOSITIONS COMPRISING 2-AMINO-1-PROPANOL AS ALKALISING AGENTS | WELLA GERMANY GMBH (DE) | 2023-02-16 | — | — | WO | claimed |
| WO-2026104266-A1 | USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2026-05-21 | — | — | WO | disclosed |
| EP-4743055-A1 | OXIDATIVE HAIR TREATMENT COMPOSITIONS COMPRISING POLYETHERS | Wella Germany GmbH (DE) | 2026-05-20 | — | — | EP | disclosed |
| EP-4739272-A1 | OXIDATIVE HAIR COLOURING COMPOSITION | Wella Germany GmbH (DE) | 2026-05-13 | — | — | EP | disclosed |
| EP-4719328-A1 | BLEACHING MEDIUM COMPRISING A PHENALENONE | Wella Germany GmbH (DE) | 2026-04-08 | — | — | EP | disclosed |
| EP-4633584-A1 | BLEACH POWDER AND METHOD FOR BLEACHING HAIR | Wella Germany GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| EP-3873407-B1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | HENKEL AG & CO KGAA (DE) | 2025-04-09 | — | — | EP | disclosed |
| WO-2025016926-A1 | OXIDATIVE HAIR TREATMENT COMPOSITIONS COMPRISING POLYETHERS | Wella GmbH (DE) | 2025-01-23 | — | — | WO | disclosed |
| WO-2025008339-A1 | OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2025-01-09 | — | — | WO | disclosed |
| WO-2024246147-A1 | BLEACHING MEDIUM COMPRISING A PHENALENONE | WELLA GERMANY GMBH (DE) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024126047-A1 | BLEACH POWDER AND METHOD FOR BLEACHING HAIR | WELLA GERMANY GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| WO-2023017039-A1 | HAIR COLORING COMPOSITIONS COMPRISING 2-AMINO-1-PROPANOL AS ALKALISING AGENTS | WELLA GERMANY GMBH (DE) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | PHOSPHO1, ALDH7A1, AASDHPPT | CHAT 821/4885KDM4E 1524/4885UBE2N 1186/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | CHAT 35/4885KDM4E 1526/4885UBE2N 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.