SCHEMBL1106832

SCHEMBL1106832

NC(=O)CCSC(CC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 1/20 0.61
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
POLB P06746 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KMT2A Q03164 2/20 0.38
ALOX15 P16050 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
CYP2C19 P33261 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2C9 P11712 1/20 0.36
TDP1 Q9NUW8 2/20 0.34
FOLH1 Q04609 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
BHMT Q93088 2/20 0.33
CYP1A2 P05177 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7798008 0.85 CPB1 (0.56) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL10933514 0.83 CPB1 (0.62) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL13241288 0.80 CPB1 (0.51) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL1106817 0.79 TDP1 (0.45) CPB1KMT2AALOX15BLMPMP22
SCHEMBL31390745 0.79 CPB1 (0.59) CPB1ALDH1A1KDM4EPOLBNPSR1
Hydrochloric Acid SCHEMBL31390753 0.78 CPB1 (0.58) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL17171976 0.76 CPB1 (0.51) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL5969702 0.76 CPB1 (0.56) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL11193696 0.76 CPB1 (0.47) CPB1ALDH1A1KDM4EPOLBNPSR1
SCHEMBL1106833 0.76 LMNA (0.48) CPB1ALDH1A1KDM4EPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318853-B2 Thermally-responsive dispersants for media formulations EASTMAN KODAK COMPANY (US) 2012-11-27 US disclosed
US-8202926-B2 Coating composition containing a dispersant EASTMAN KODAK COMPANY (US) 2012-06-19 US disclosed
US-8153716-B2 Dispersant for an aqueous dispersion of positively charged or chargeable solid particulates which comprises a compound having an anchoring moiety linked to a polymeric hydrophilic moiety; inkjet recording element EASTMAN KODAK COMPANY (US) 2012-04-10 US disclosed
US-8063132-B2 Coating composition comprising boehmite particles and one or more dispersants and a method of coating a substrate using said coating composition EASTMAN KODAK COMPANY (US) 2011-11-22 US disclosed
US-20100184910-A1 THERMALLY-RESPONSIVE DISPERSANTS FOR MEDIA FORMULATIONS BANK OF AMERICA, N.A., AS AGENT 2010-07-22 US disclosed
US-20080317960-A1 Dispersant for Reducing Viscosity of Solids FPC INC. 2008-12-25 US disclosed
US-20080145546-A1 Dispersant For Reducing Viscosity Of Particulate Solids FPC INC. 2008-06-19 US disclosed
US-20080090012-A1 Aqueous boehmite particles of a hydrophilic polymer having a linked anchoring moiety which contains acid(s) and/or hydroxy(s); the polymeric moiety has a lower affinity for a boehmite surface than the anchoring moiety; mercaptosuccinic acid-modified polyacrylamide; ink jet; paper coating; gloss porousity KODAK PHILIPPINES LTD. 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090012-A1 Aqueous boehmite particles of a hydrophilic polymer having a linked anchoring moiety which contains acid(s) and/or hydroxy(s); the polymeric moiety has a lower affinity for a boehmite surface than the anchoring moiety; mercaptosuccinic acid-modified polyacrylamide; ink jet; paper coating; gloss porousity CD44, MPST, BHMT2 CPB1 4252/4885ALDH1A1 320/4885KDM4E 1517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.