Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056072 | 0.81 | MAPT (0.48) | ABL1ABCB1BCRKDM4EPTPN1 | |
| SCHEMBL11566163 | 0.77 | TDP1 (0.52) | ABL1TDP1GAAKMT2AMEN1 | |
| SCHEMBL6277589 | 0.77 | TDP1 (0.52) | ABL1TDP1GAAKMT2AMEN1 | |
| SCHEMBL30023288 | 0.74 | GAA (0.57) | ABL1TDP1GAAKMT2AMEN1 | |
| SCHEMBL11652329 | 0.74 | GAA (0.57) | ABL1TDP1GAAKMT2AMEN1 | |
| SCHEMBL28470699 | 0.73 | TDP1 (0.67) | TDP1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL1014744 | 0.73 | TDP1 (0.67) | TDP1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL6475331 | 0.72 | KMT2A (0.46) | ABL1TDP1ABCB1BCRGAA | |
| SCHEMBL10749005 | 0.71 | TDP1 (0.42) | ABL1TDP1GAAKMT2AMEN1 | |
| SCHEMBL11653951 | 0.71 | GAA (0.44) | TDP1GAAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486344-A | CARBONYLDIIMIDAZOLE AS LINKING AGENT, IMMUNOASSY | MILES LABORATORIES, INC. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0123114-A1 | Urea-linked immunogens, antibodies, and preparative method | MILES LABORATORIES, INC. (US) | 1984-10-31 | — | — | EP | disclosed |