Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068574 | 0.81 | ABL1 (0.43) | MAPTALDH1A1KDM4EHPGDABL1 | |
| SCHEMBL8595564 | 0.76 | POLB (0.63) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30550385 | 0.76 | POLB (0.63) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7167696 | 0.76 | ALDH1A1 (0.67) | MAPTALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL11653846 | 0.72 | ALOX15 (0.59) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11650712 | 0.72 | LMNA (0.56) | MAPTALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL11649213 | 0.71 | GAA (0.48) | MAPTALDH1A1KDM4ETP53TSHR | |
| SCHEMBL11644988 | 0.71 | ALOX15 (0.46) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11060023 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL20681467 | 0.71 | TNKS2 (0.60) | MAPTALDH1A1KDM4EHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486344-A | CARBONYLDIIMIDAZOLE AS LINKING AGENT, IMMUNOASSY | MILES LABORATORIES, INC. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0123114-A1 | Urea-linked immunogens, antibodies, and preparative method | MILES LABORATORIES, INC. (US) | 1984-10-31 | — | — | EP | disclosed |