Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.44 |
| ▸ | DRD3 | P35462 | 7/20 | 0.44 |
| ▸ | DRD4 | P21917 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071420 | 0.91 | DRD2 (0.47) | DRD2DRD3DRD4KCNH2HTR7 | |
| SCHEMBL11071740 | 0.89 | HTR7 (0.50) | DRD2DRD3DRD4HTR7MAOA | |
| SCHEMBL11064990 | 0.89 | DRD2 (0.51) | DRD2DRD3DRD4KCNH2HTR7 | |
| SCHEMBL11068604 | 0.89 | KCNH2 (0.53) | DRD2DRD3DRD4KCNH2HTR7 | |
| SCHEMBL11070967 | 0.87 | DRD2 (0.53) | DRD2DRD3DRD4HTR7MAOA | |
| SCHEMBL11063280 | 0.86 | DRD2 (0.53) | DRD2DRD3DRD4KCNH2HTR7 | |
| SCHEMBL11073453 | 0.85 | DRD2 (0.44) | DRD2DRD3DRD4KCNH2HTR7 | |
| SCHEMBL11071326 | 0.85 | DRD2 (0.47) | DRD2DRD3DRD4HTR7MAOA | |
| SCHEMBL11065769 | 0.85 | DRD2 (0.58) | DRD2DRD3DRD4KCNH2HTR7 | |
| SCHEMBL11069074 | 0.84 | HTR7 (0.46) | DRD2DRD3DRD4HTR7ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |