Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NGFR | P08138 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065167 | 0.86 | GPR35 (0.64) | GLAGAAGPR35CYP1A2NGFR | |
| SCHEMBL11723446 | 0.81 | GPR35 (0.68) | GLAGAAGPR35MAPTXDH | |
| SCHEMBL11262250 | 0.81 | MAPT (0.35) | GPR35MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL11256783 | 0.78 | GPR35 (0.40) | GPR35MAPTPDE2APDE1APDE1B | |
| SCHEMBL11640545 | 0.73 | GPR35 (0.64) | GLAGAAGPR35MAPTCYP1A2 | |
| SCHEMBL10918772 | 0.72 | GLA (0.44) | GLAGAAGPR35MAPTXDH | |
| SCHEMBL11638566 | 0.72 | GLA (0.58) | GLAGAAGPR35MAPTXDH | |
| SCHEMBL2903161 | 0.71 | GLA (0.51) | GLAGAAGPR35MAPTXDH | |
| SCHEMBL11721616 | 0.71 | GLA (0.61) | GLAGAAGPR35MAPTXDH | |
| SCHEMBL11725265 | 0.71 | GLA (0.57) | GLAGAAGPR35MAPTXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |