Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARS1 | P26639 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073039 | 0.89 | TARS1 (0.36) | TARS1PTGS1F2F10PRSS1 | |
| SCHEMBL11066689 | 0.85 | TARS1 (0.39) | TARS1PTGS1F2F10PRSS1 | |
| SCHEMBL11468020 | 0.84 | PTGS1 (0.36) | PTGS1HSD17B14MEN1CYP2D6KMT2A | |
| SCHEMBL11281589 | 0.81 | L3MBTL1 (0.32) | PTGS1HSD17B14ADAMTS4 | |
| SCHEMBL11275766 | 0.81 | HSD17B14 (0.31) | PTGS1HSD17B14MEN1KMT2AADAMTS4 | |
| SCHEMBL11274780 | 0.81 | ALDH1A1 (0.31) | PTGS1ADAMTS4 | |
| SCHEMBL11265443 | 0.80 | L3MBTL1 (0.31) | PTGS1 | |
| SCHEMBL11275008 | 0.78 | ADAMTS4 (0.31) | ADAMTS4 | |
| SCHEMBL11492578 | 0.78 | ALDH1A1 (0.36) | PTGS1F2F10PRSS1PRSS2 | |
| SCHEMBL11070361 | 0.78 | ADAMTS4 (0.33) | ADAMTS4MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |