Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810212 | 0.82 | KMT2A (0.47) | KDM4EPTGDR2ABCB1ALDH1A1MEN1 | |
| SCHEMBL6252152 | 0.81 | ALDH1A1 (0.49) | LMNAKDM4ECYP1A2SMN1; SMN2TDP1 | |
| SCHEMBL28853260 | 0.72 | L3MBTL1 (0.46) | LMNAKDM4ECYP1A2SMN1; SMN2TDP1 | |
| SCHEMBL11069025 | 0.71 | MAOB (0.39) | LMNAKDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL130085 | 0.68 | GAA (0.49) | LMNAKDM4ECYP1A2SMN1; SMN2TDP1 | |
| SCHEMBL9198757 | 0.68 | ABCB1 (0.48) | CYP1A2TDP1L3MBTL1ABCB1HPGD | |
| Catechol SCHEMBL9787047 | 0.68 | ESR1 (0.57) | ESR1ESR2LMNAKDM4ECYP1A2 | |
| SCHEMBL864716 | 0.67 | MAPT (0.61) | ESR1ESR2LMNAKDM4ECYP1A2 | |
| SCHEMBL9787116 | 0.67 | L3MBTL1 (0.65) | ESR1ESR2LMNASMN1; SMN2TDP1 | |
| SCHEMBL27499328 | 0.67 | LMNA (0.48) | LMNAKDM4ECYP1A2SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474788-A | Anti-SRSA quinoline carboxylic acid derivatives | FISONS PLC (GB) | 1984-10-02 | — | — | US | disclosed |
| EP-0079637-A1 | Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them | FISONS plc (GB) | 1983-05-25 | — | — | EP | disclosed |