Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078596 | 0.83 | OPRL1 (0.72) | OPRL1SLC6A4OPRM1SLC6A2OPRD1 | |
| SCHEMBL5469627 | 0.81 | KMT2A (0.61) | OPRL1MEN1NPC1GAAMAPT | |
| SCHEMBL5469632 | 0.81 | KMT2A (0.61) | OPRL1MEN1NPC1GAAMAPT | |
| Hydrochloric Acid SCHEMBL11075754 | 0.81 | OPRL1 (1.00) | OPRL1OPRM1KDM1AOPRK1 | |
| SCHEMBL11073243 | 0.77 | OPRL1 (0.51) | OPRL1MAPK1SLC6A4OPRM1SLC6A2 | |
| SCHEMBL20888167 | 0.77 | SLC6A4 (0.50) | OPRL1MEN1KMT2ASLC6A4OPRM1 | |
| SCHEMBL11075826 | 0.76 | OPRL1 (0.50) | OPRL1MAPTMAPK1SLC6A4OPRM1 | |
| SCHEMBL11069061 | 0.75 | OPRL1 (0.75) | OPRL1MAPTKMT2AALDH1A1 | |
| SCHEMBL11076744 | 0.74 | OPRL1 (0.47) | OPRL1MEN1NPC1GAAMAPT | |
| SCHEMBL11075824 | 0.74 | OPRL1 (0.47) | OPRL1MEN1NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |