Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11073610 | 0.99 | OPRL1 (0.76) | OPRL1ALDH1A1KDM4ESMN1; SMN2EPHX2 | |
| Hydrochloric Acid SCHEMBL11075754 | 0.84 | OPRL1 (1.00) | OPRL1 | |
| SCHEMBL11078596 | 0.76 | OPRL1 (0.72) | OPRL1IRAK4 | |
| SCHEMBL11078979 | 0.75 | OPRL1 (0.45) | OPRL1ALDH1A1KMT2AMAPTCCR1 | |
| SCHEMBL11069247 | 0.75 | OPRL1 (0.69) | OPRL1ALDH1A1KMT2AMAPT | |
| SCHEMBL11075757 | 0.73 | OPRL1 (0.43) | OPRL1KMT2ACCR1 | |
| SCHEMBL11244959 | 0.72 | SLC6A3 (0.47) | OPRL1 | |
| SCHEMBL11074296 | 0.72 | OPRL1 (0.42) | OPRL1KMT2ACCR1 | |
| SCHEMBL11072870 | 0.72 | OPRL1 (0.42) | OPRL1KMT2ACCR1 | |
| SCHEMBL4352646 | 0.72 | OPRL1 (0.97) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | claimed |
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |