Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.72 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077290 | 0.86 | OPRD1 (0.55) | OPRL1OPRD1OPRK1OPRM1 | |
| SCHEMBL11066160 | 0.86 | OPRL1 (0.54) | OPRL1OPRM1TACR1SLC6A4 | |
| SCHEMBL11069247 | 0.83 | OPRL1 (0.69) | OPRL1OPRD1OPRK1OPRM1SLC6A2 | |
| SCHEMBL11081934 | 0.83 | OPRL1 (0.51) | OPRL1OPRD1OPRK1OPRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11075754 | 0.83 | OPRL1 (1.00) | OPRL1OPRK1OPRM1TACR1 | |
| SCHEMBL11074165 | 0.77 | OPRL1 (0.44) | OPRL1OPRK1OPRM1 | |
| SCHEMBL11069061 | 0.76 | OPRL1 (0.75) | OPRL1IRAK4 | |
| SCHEMBL11079767 | 0.76 | OPRD1 (0.49) | OPRL1OPRD1OPRK1OPRM1TACR1 | |
| SCHEMBL11076919 | 0.75 | OPRL1 (0.43) | OPRL1OPRD1OPRK1OPRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11073610 | 0.75 | OPRL1 (0.76) | OPRL1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |