Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631751 | 0.77 | ALDH1A1 (0.37) | TSHRIDO1AGXTALDH1A1TP53 | |
| SCHEMBL10831876 | 0.76 | ALDH1A1 (0.40) | TSHRIDO1AGXTALDH1A1TP53 | |
| SCHEMBL11064974 | 0.76 | KCNA3 (0.34) | TSHRALDH1A1TP53 | |
| SCHEMBL1726956 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TP53 | |
| SCHEMBL29326171 | 0.75 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1HTR1A | |
| SCHEMBL11069547 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL2473034 | 0.70 | TSHR (0.64) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL1117737 | 0.69 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL28546165 | 0.69 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9637850 | 0.69 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446061-A | FIREPROOFING, SMOKELESS, PHOSPHITE/PHOSPHONATE | MONSANTO COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4260542-A | FLAME RETARDANTS, SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4206133-A | FLAME RETARDANTS AND SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| US-4133823-A | FIREPROOFING, SMOKELESS | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |