Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168558 | 0.95 | CYSLTR2 (0.51) | PTGS2POLBCXCL8CYSLTR2CYSLTR1 | |
| SCHEMBL9780647 | 0.94 | CYSLTR2 (0.50) | PTGS2POLBCXCL8CYSLTR2CYSLTR1 | |
| SCHEMBL11069348 | 0.89 | CYP2C9 (0.46) | PTGS2POLBCXCL8CYSLTR2CYSLTR1 | |
| SCHEMBL11065929 | 0.86 | SOAT2 (0.49) | POLBCYSLTR2CYSLTR1PTGS1CYP2C9 | |
| SCHEMBL11069324 | 0.86 | SOAT2 (0.49) | POLBCYSLTR2CYSLTR1PTGS1CYP2C9 | |
| SCHEMBL11072836 | 0.86 | SOAT2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL11065936 | 0.86 | SOAT2 (0.49) | POLBCYSLTR2CYSLTR1PTGS1CYP2C9 | |
| SCHEMBL11069327 | 0.86 | SOAT2 (0.49) | POLBCYSLTR2CYSLTR1PTGS1CYP2C9 | |
| SCHEMBL11072831 | 0.86 | SOAT2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL11819008 | 0.83 | PTGS2 (0.57) | PTGS2POLBCXCL8NR1H4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139611-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | MILESTONE PHARMACEUTICALS, INC. (CA) | 2008-06-12 | — | — | US | disclosed |
| WO-2008048577-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | MILESTONE PHARMACEUTICALS INC. (CA) | 2008-04-24 | — | — | WO | disclosed |
| EP-0970087-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998045300-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139611-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | PTGES2, NFKBIA, PTGES | PTGS2 8/4885POLB 2390/4885CXCL8 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.