SCHEMBL11069418

SCHEMBL11069418

CC(=O)Nc1cc(N)c(Cl)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 4/20 0.47
PGK1 P00558 1/20 0.46
ROCK2 O75116 1/20 0.45
NPC1 O15118 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC3 O15379 1/20 0.44
HDAC2 Q92769 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9137511 0.92 CA1 (0.50) CA1CA2CA9ALDH1A1PGK1
SCHEMBL8610558 0.90 CA1 (0.47) CA1CA2CA9ALDH1A1PGK1
Butanedione SCHEMBL28088921 0.89 CA1 (0.47) CA1CA2CA9ALDH1A1PGK1
SCHEMBL8777806 0.85 CA1 (0.44) CA1CA2CA9ALDH1A1NPC1
SCHEMBL6202482 0.84 CA1 (0.46) CA1CA2CA9ALDH1A1NPC1
SCHEMBL7684726 0.84 CA1 (0.46) CA1CA2CA9ALDH1A1PGK1
SCHEMBL18331700 0.84 CA1 (0.46) CA1CA2CA9ALDH1A1PGK1
SCHEMBL202652 0.84 ALDH1A1 (0.53) CA1CA2CA9ALDH1A1PGK1
Acetoacetic Acid SCHEMBL11803776 0.82 PGK1 (0.43) CA1CA2CA9ALDH1A1PGK1
SCHEMBL8021721 0.81 CA1 (0.51) CA1CA2CA9ALDH1A1PGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315744-B In the sulfenamide Synthesis method of intermediate 浙大宁波理工学院 2024-09-13 CN claimed
CN-114149375-B Intermediate for synthesizing sulfenamide and synthesis method thereof 浙大宁波理工学院 2024-09-03 CN claimed
CN-118290299-A 2- (2- (5-Acetamido-2, 4-dichlorophenyl) hydrazono) propionic acid compound 浙大宁波理工学院 2024-07-05 CN claimed
CN-118084716-A N- (2, 4-dichloro-5-hydrazinophenyl) acetamide compound 浙大宁波理工学院 2024-05-28 CN claimed
CN-114181162-B Preparation method of sulfonyl carfentrazone-ethyl 浙大宁波理工学院 2024-04-16 CN claimed
CN-114044758-B Synthetic method of intermediate for preparing triazolinone herbicide sulfenamide 浙大宁波理工学院 2024-03-26 CN claimed
CN-114057659-B Intermediate for synthesizing sulfenamide and synthesis method thereof 浙大宁波理工学院 2024-03-26 CN claimed
CN-114315744-A Synthetic method of sulfentrazone intermediate 浙大宁波理工学院 2022-04-12 CN claimed
CN-114276306-A Synthetic method of sulfentrazone 浙大宁波理工学院 2022-04-05 CN claimed
CN-114181162-A Preparation method of sulcarfentrazone-ethyl 浙大宁波理工学院 2022-03-15 CN claimed
CN-114149375-A Intermediate for synthesizing sulfentrazone and synthesis method thereof 浙大宁波理工学院 2022-03-08 CN claimed
CN-114149342-A N- (2, 4-dichloro-5-hydrazinophenyl) acetamide compound and synthesis method thereof 浙大宁波理工学院 2022-03-08 CN claimed
CN-114057659-A Intermediate for synthesizing sulfentrazone and synthesis method thereof 浙大宁波理工学院 2022-02-18 CN claimed
CN-114044758-A Synthesis method of intermediate for preparing triazolinone herbicide sulfentrazone 浙大宁波理工学院 2022-02-15 CN claimed
CN-114031520-A 2- (2- (5-acetamido-2, 4-dichlorophenyl) hydrazono) propionic acid compound and synthetic method thereof 浙大宁波理工学院 2022-02-11 CN claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
CN-114315744-B In the sulfenamide Synthesis method of intermediate 浙大宁波理工学院 2024-09-13 CN disclosed
CN-114149375-B Intermediate for synthesizing sulfenamide and synthesis method thereof 浙大宁波理工学院 2024-09-03 CN disclosed
US-4080321-A COLORFASTNESS HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-21 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed