Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075815 | 0.86 | ADAM17 (0.42) | ALOX5ADAM17MAOBHTR1ADRD1 | |
| SCHEMBL11073748 | 0.83 | ALOX5 (0.55) | ALOX5ADAM17MAOBHTR1ADRD1 | |
| Ethylene SCHEMBL11074499 | 0.81 | ALOX5 (0.53) | ALOX5ADAM17MAOBHTR1ADRD1 | |
| SCHEMBL11077399 | 0.81 | KMT2A (0.42) | — | |
| SCHEMBL11071018 | 0.81 | ALOX5 (0.52) | ALOX5ADAM17MAOBHTR1ADRD1 | |
| Ethylene SCHEMBL11556258 | 0.80 | ALOX5 (0.46) | ALOX5ADAM17MAOBCYP2D6HPD | |
| SCHEMBL11097718 | 0.80 | ALDH1A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL11099779 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL11089351 | 0.80 | DRD3 (0.43) | — | |
| SCHEMBL11093324 | 0.79 | DRD3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |