Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069574 | 0.84 | KDM4E (0.46) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL5257685 | 0.75 | KDM4E (0.50) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL6636369 | 0.73 | PRMT5 (0.50) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL30625771 | 0.73 | MMP2 (0.46) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL28008057 | 0.73 | METAP2 (0.46) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL28552136 | 0.70 | MAPT (0.57) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL28182820 | 0.69 | PRMT5 (0.42) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL28579187 | 0.69 | PRMT5 (0.42) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL30620972 | 0.69 | PRMT5 (0.42) | KDM4ENPC1RAB9AMAPTPKM | |
| SCHEMBL3499713 | 0.66 | TOP1 (0.53) | KDM4ENPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353824-A | DETECTORS OF BETA-LACTAMASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | claimed |
| US-4448880-A | Detection of β-lactamase utilizing a chromophoric cephalosporin composition | HOECHST AG. (DE) | 1984-05-15 | — | — | US | disclosed |
| US-4353824-A | DETECTORS OF BETA-LACTAMASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |