Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074078 | 0.83 | GRIN2B (0.40) | GRIN2BSLC18A3OPRM1OPRL1CHIA | |
| SCHEMBL11077902 | 0.82 | SLC6A4 (0.39) | OPRM1OPRL1SIGMAR1DRD2HTR2A | |
| SCHEMBL11069827 | 0.78 | GRIN2B (0.42) | GRIN2BSLC18A3OPRM1OPRL1CHIA | |
| SCHEMBL11065445 | 0.78 | OPRM1 (0.58) | GRIN2BSLC18A3OPRM1OPRL1CHIA | |
| SCHEMBL1967143 | 0.78 | GRIN2B (0.63) | GRIN2BSLC18A3OPRM1CHIASIGMAR1 | |
| SCHEMBL11066830 | 0.77 | OPRL1 (0.46) | GRIN2BSLC18A3OPRM1OPRL1CHIA | |
| SCHEMBL11078301 | 0.76 | OPRL1 (0.58) | GRIN2BOPRM1OPRL1 | |
| SCHEMBL11073158 | 0.75 | OPRM1 (0.50) | GRIN2BOPRM1OPRL1DRD2OPRK1 | |
| SCHEMBL27820511 | 0.75 | SLC18A3 (0.64) | GRIN2BSLC18A3OPRM1CHIASIGMAR1 | |
| SCHEMBL11079938 | 0.74 | OPRL1 (0.46) | GRIN2BOPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |