Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.41 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.41 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.41 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065445 | 0.81 | OPRM1 (0.58) | OPRL1OPRM1GRIN2BSLC18A3CHIA | |
| SCHEMBL11080641 | 0.81 | POLB (0.41) | OPRL1OPRM1GRIN2BSLC18A3 | |
| SCHEMBL11073158 | 0.81 | OPRM1 (0.50) | OPRL1OPRM1GRIN2B | |
| SCHEMBL11076128 | 0.81 | CHIA (0.44) | OPRL1OPRM1GRIN2BSLC18A3CHIA | |
| SCHEMBL11073826 | 0.80 | GRIN2B (0.43) | OPRL1OPRM1GRIN2BSLC18A3CHIA | |
| SCHEMBL11078301 | 0.79 | OPRL1 (0.58) | OPRL1OPRM1GRIN2B | |
| SCHEMBL11077368 | 0.79 | GRIN2B (0.42) | OPRL1OPRM1GRIN2BSLC18A3CHIA | |
| SCHEMBL11073738 | 0.78 | SLC6A3 (0.49) | OPRL1OPRM1NOS3NOS1NOS2 | |
| SCHEMBL11079938 | 0.77 | OPRL1 (0.46) | OPRL1OPRM1GRIN2B | |
| SCHEMBL11069648 | 0.77 | GRIN2B (0.47) | OPRL1OPRM1GRIN2BSLC18A3CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |