Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | PDE1A | P54750 | 2/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747539 | 0.86 | ADORA3 (0.50) | CHEK1ADORA1PDE3BPDE3APDE5A | |
| SCHEMBL10742951 | 0.84 | KDM4E (0.42) | CHEK1SMN1; SMN2KDM4EALDH1A1AURKA | |
| SCHEMBL10746357 | 0.83 | KDM4E (0.49) | LMNACHEK1ADORA1DAOPDE3B | |
| SCHEMBL10745926 | 0.81 | CYP2C9 (0.40) | LMNACHEK1ADORA1PDE3BPDE3A | |
| SCHEMBL10744610 | 0.81 | PARP10 (0.49) | CHEK1DAOPDE3BPDE3APDE2A | |
| SCHEMBL10746913 | 0.81 | PARP10 (0.49) | CHEK1DAOPDE3BPDE3APDE2A | |
| SCHEMBL10743293 | 0.80 | MTNR1B (0.42) | CHEK1ADORA1PDE3BPDE3APDE2A | |
| SCHEMBL10745368 | 0.76 | CYP1A2 (0.40) | PDE2AALDH1A1BLMKMT2A | |
| SCHEMBL10745104 | 0.76 | KDM4E (0.40) | ADORA1SMN1; SMN2KDM4EALDH1A1ADORA3 | |
| SCHEMBL10742152 | 0.75 | FEN1 (0.39) | CHEK1ADORA1DAOPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039920-B1 | TRIAZALOQUINOXALIN-1,4-DIONES | USV PHARMACEUTICAL CORPORATION (US) | 1984-07-25 | — | — | EP | claimed |
| EP-0039920-A2 | Triazaloquinoxalin-1,4-diones | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-18 | — | — | EP | claimed |