Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742951 | 0.83 | KDM4E (0.42) | CHEK1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10743293 | 0.82 | MTNR1B (0.42) | ADORA1CHEK1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11069723 | 0.81 | LMNA (0.44) | ADORA1CHEK1ALDH1A1KDM4ERET | |
| SCHEMBL10744610 | 0.77 | PARP10 (0.49) | CHEK1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL10746913 | 0.77 | PARP10 (0.49) | CHEK1ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL10747539 | 0.75 | ADORA3 (0.50) | ADORA1CHEK1RETSMN1; SMN2PDE3B | |
| SCHEMBL10744197 | 0.75 | KDM4E (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2GLA | |
| SCHEMBL10745104 | 0.72 | KDM4E (0.40) | ADORA1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10745368 | 0.72 | CYP1A2 (0.40) | CYP2C9ALDH1A1KMT2ACYP1A2 | |
| Potassium Ion SCHEMBL10743069 | 0.70 | ALDH1A1 (0.37) | CHEK1ALDH1A1KDM4ESMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668678-A | ANTIALLERGENS | USV PHARMACEUTICAL CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| US-4507300-A | Pyridotriazolopyrazine-diones for treating allergy | USV PHARMACEUTICAL CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4400382-A | Thiazoloquinoxalin-1,4-diones for treating allergy | USV PHARMACEUTICAL CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0039920-A2 | Triazaloquinoxalin-1,4-diones | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-18 | — | — | EP | disclosed |