Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eflumast SCHEMBL1230501 | 0.83 | PKM (0.32) | RXFP1NPC1 | |
| SCHEMBL10516283 | 0.83 | CYP1A2 (0.37) | NPC1ALDH1A1 | |
| SCHEMBL11072324 | 0.82 | CYP1A2 (0.30) | — | |
| SCHEMBL11067331 | 0.82 | MEN1 (0.35) | ALDH1A1 | |
| SCHEMBL11074597 | 0.81 | LMNA (0.36) | NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11065854 | 0.81 | — | — | |
| SCHEMBL11076161 | 0.80 | CYP1A2 (0.36) | ALDH1A1 | |
| SCHEMBL10513959 | 0.80 | LMNA (0.32) | — | |
| SCHEMBL10513044 | 0.79 | TTR (0.35) | RXFP1 | |
| SCHEMBL11073859 | 0.78 | AKR1B1 (0.42) | NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |